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241 Because of its central role in methylation, Met is considered a candidate target for tumor therapy driven by ten-eleven translocation (TET), isocitrate dehydrogenase (IDH) proteins, methyltransferases, and other phenotypic modifiers

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Factors contributing to the increased susceptibility of OLs to oxidative stress include the high intracellular iron content of the cells and relatively low levels of endogenous antioxidant proteins, which are lower in OPCs compared with mature OLs [14,15,23,24]

In this population, different features, such as oxidative stress, inflammation, energy depletion, and uremic toxins, may exacerbate eryptosis [208, 231, 247]

185,194 Furthermore, ZnT2 is indispensable for the development of lysosome biogenesis and bacterial-stimulated autophagy, 195 facilitating a powerful host defense and resolution machinery against enteric pathogens