melanotic pigmentation Characteristic peri-oral more pronounced on the Smokers melanosis . Oral pigmentation

Smokers melanosis . Oral pigmentation seen in heavy smokers . Investigations have shown ability of melanin to bind to noxious substances. . Exposure to polycyclic amines ( Nicotine & benzpyrene) has shown Melanotic Macules, Naevi, and Melanoma Springer Nature Link Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review PMC Definition of melanocytic macules associated with Peutz Jeghers syndrome NCI Dictionary of Genetics Terms NCI Oral Melanotic Macule: Symptoms and Treatment Skinsight

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