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Another important function of this protein is binding to drugs to make them more soluble for excretion

Chemical Biology of H2S Signaling through Persulfidation

CDK9 inhibition blocks the initiation of PINK1-PRKN-mediated mitophagy by regulating the SIRT1-FOXO3-BNIP3 axis and enhances the therapeutic effects involving mitochondrial dysfunction in hepatocellular carcinoma

In some patients, vomiting episodes become less frequent when these cofactors are used alone

Its anti-fibrotic action makes it particularly well-studied in models of chronic injury, cardiac fibrosis, and musculoskeletal lesions (Malinda et al., J Invest Dermatol 1999)