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doi: 10.1038/s41467-019-12313-3 79 Rios de la RosaJ

doi: 10.1016/j.bcp.2017.09.010

Kabiri M, Steverding D

Excessive ROS serve not only as a direct agent causing damage to biological macromolecules but also as a potent second messenger that activates key pro-inflammatory signaling pathways, such as NF-B and MAPK, through the oxidative modification of essential signaling proteins (62)