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This appeared as a direct consequence of the retrobulbar L-NAME application

adaptation to starch-rich diets 6

Contrary to the two models of halogenation in NRP biosynthesis presented above where halogenation occurs either on free amino acids or en route peptide assembly, chlorination during the biosynthesis of the RiPP antibiotic NAI-107 occurs after all other modifications on the RiPP precursor peptide have been installed, and the post-translationally modified C-terminal core has been proteolytically removed from the unmodified N-terminal core peptide [1, 42]

Patient age was the most common exclusion criteria used in trials, with over half the trials excluding patients over the age of 55 or under the age of 18 (Fig

degrades under exposure to light and UV