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Scand J Urol 2016;50:267273

Ca2+ provides favorable features as a secondary messenger and serves as one of the major components in the cellular signaling pathways of many organisms (Sanders et al., 1999)

While GLP-1 agonists primarily target appetite and gastric emptying, tirzepatide is studied for its additional GIP receptor effectsparticularly on adipose tissue metabolism and potentially enhanced insulin secretion