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Regarding -syn aggregates, all oligomeric -syn species induce a dramatic immune cell activation, showing a correlation between the molecular weight of oligomers and the intensity of the response, with -syn fibrils producing the most powerful activation of monocytes [64]

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A single chimeric transgene was created by combining partial sense sequences for all possible permutations of the lignin genes, including caffeate/5-hydroxyferulate O-methyltransferase (COMT), cinnamoyl alcohol dehydrogenase (CAD), and cinnamoyl-coenzyme A reductase (CCR)

doi: 10.1016/j.plaphy.2022.06.021 2 AnJ