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But even in those, the effect sizes are relatively small, and in the clinic the results are often more disappointing than the trials would suggest. Dr Whittle said due to the nature of fibromyalgia, there was unlikely to be a magic bullet or single receptor pharmacotherapeutic intervention that was broadly or substantially successful in most people with fibromyalgia

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The treatment also led to improvements in waist circumference, waist-to-hip ratio, and body image, without affecting blood sugar levels or causing major side effects

Simeons in 1954

This is valuable for educational discussions about trial design, dosing ranges, and peptide behaviour