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TRAF6-mediated SM22 K21 ubiquitination promotes G6PD activation and NADPH production, contributing to GSH homeostasis and VSMC survival in vitro and in vivo

doi: 10.1038/s42255-025-01245-6 108 Mazloum-RavasanSMadadiEMohammadiAMansooriBAminiMMokhtarzadehAet al

196 Juma et al

Detoxification & Wellness: Aids in the natural detoxification process, promoting overall health and vitality

It was also found that the Michaelis constant (Km = 1.2 10 5 M) of FSP1 was relatively low, and the maximum reaction rate (Vmax = 4.1 10 7 M s 1) was much higher than that of related oxidoreductases, indicating that efficiency of FSP1