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[10] [12] High doses of ascorbic acid can increase the absorption of iron from the gastrointestinal tract and may potentiate the effects of oral iron supplementation or exacerbate iron overload in susceptible individuals

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[8] Similarly, patients with gout or hyperuricemia should avoid high niacin intake, as niacin (even in nicotinamide form) can raise uric acid levels and potentially trigger gout flares

Vitamin B12 is essential for: Energy production Red blood cell formation Nervous system function Brain health and concentration When B12 levels are low, the body struggles to produce energy efficiently, leading to fatigue and other symptoms

p38 MAP kinase inhibition ameliorates cisplatin nephrotoxicity in mice