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Round cell sarcomas beyond Ewing: emerging entities

Int J Mol Sci 15:16471670

19 Gab1 recruits and activates phosphoinositide 3-kinase (PI3K) that converts PIP2 (phosphatidylinositol-4, 5-bisphosphate) to PIP3 (phosphatidylinositol-3, 4, 5-triphosphate), which goes on to phosphorylate Akt

Possible new role for nf-kappab in the resolution of inflammation

This helps transition the injury from the inflammatory phase to the proliferative and remodeling phases more efficiently, without the need for NSAIDs that may impair certain aspects of tissue healing