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Its important to note that while DBT therapy is effective for various conditions, individual responses may vary, and its application may be tailored to specific needs

In contrast, substitution to an amidated proline instead of an amidated tyrosine in the C-terminus of rAmy is well tolerated, resulting in enhanced affinity and activity at both the CTR and AMYRs, but, in some cases, reduced selectivity between these receptors 18