Table 2 Muscle and Cartilage Repair Therapeutic Peptides and Molecular Pathways Growth Hormone Secretagogues: Ipamorelin, CJC-1295, Tesamorelin, and Sermorelin GH secretagogues are synthetic peptides that stimulate the pituitary gland to increase endogenous growth hormone secretion
Abbreviations EOC: Epithelial ovarian cancer OCCC: Ovarian clear cell carcinoma OEC: Endometrioid carcinoma ARID1A: AT-rich interactive domain-containing protein 1A PIK3CA: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha PTEN: Phosphatase and tensin homolog KRAS: KRAS proto-oncogene TP53: Tumor protein p53 EAOC: Endometriosis-associated ovarian cancer SIR: Standardized incidence ratio CI: Confidence interval ER: Estrogen receptor beta ER: Estrogen receptor alpha BDNF: Brain-derived neurotrophic factor TrkB: Tropomyosin receptor kinase B (NTRK2) IHC: Immunohistochemistry ERE: Estrogen response element RTK: Receptor tyrosine kinase PI3K: Phosphatidylinositol 3-kinase AKT: Protein kinase B EMT: Epithelialmesenchymal transition TME: Tumor microenvironment MAPK/ERK: Mitogen-activated protein kinase/extracellular signal-regulated kinase JAK/STAT: Janus kinase/signal transducer and activator of transcription OR: Odds ratio HR: Hazard ratio IC50: Half maximal inhibitory concentration p-AKT: Phosphorylated AKT p-ERK: Phosphorylated ERK mTOR: Mechanistic target of rapamycin FFPE: Formalin-fixed, paraffin-embedded References Pearce CL, Templeman C, Rossing MA, Lee A, Near AM, Webb PM, Nagle CM, Doherty JA, Cushing-Haugen KL, Wicklund KG
Hidradenitis suppurativa (HS) prevalence, demographics and management pathways in Australia: a population-based cross-sectional study
Both are complementary in multi-tissue protocols, with non-redundant mechanisms
This peptide is referenced in scientific literature for studies involving telomere regulation, DNA stability, circadian rhythm signaling, and cellular mechanisms
