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The unique pathological microenvironment of DWincluding persistently high ROS levels, high protease activity, and pH fluctuationsposes significant challenges to drug stability, retention, and bioactivity

Our skin is the organ most exposed to this damage, and as a result, it becomes dull, pigmented, and loses its elasticity

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Vitvitsky et al., 2006), leading to prevention and possible amelioration of AD-associated cognitive decline (Haddad et al., 2021)

Altogether, these data indicate that GSH is differentially important in FoB and MZB at steady state, and that MZB show higher dependency on GSH upon in vitro activation