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Clinically, this manifests as peripheral neuropathy, characterized by numbness, painful tingling, burning sensations in the extremities, and eventual loss of motor function

The kinetic constants (K M and V max ) were obtained according to MichaelisMenten equation: V = V max [S]/(K M + [S]) (1), where V was the initial velocity, [S] was the concentration of the substrate, K M was the MichaelisMenten constant, and V max was the maximal reaction velocity

AOD-9604 is an artificial fragment of the GH C-terminal peptide

Glutathione is actually found in high concentrations in the placenta

Research has demonstrated that NCOA4 knockdown reduces intracellular iron levels and lipid peroxidation, thereby attenuating zinc nanoparticle-induced cell death (70)