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Brendan Vermeire is a Mental and Metabolic Health Scientist, Functional Medicine Educator, and Board-Certified Holistic Health Practitioner

AhR, Aryl hydrocarbon receptor

Tryptophan metabolites-indole derivatives (for example, indole-3-lactic acid, indole-3-acetic acid) and kynurenine pathway metabolites (kynurenine, kynurenic acid, 3-hydroxykynurenine)-are synthesized by gut bacteria (for example, Clostridium sporogenes, Lactobacillus spp.) via tryptophanase or indoleamine-2,3-dioxygenase

Similarly, Brachypodium APX3 knockdown line (JJ22251) transformed with the same pJJ2LBA vector has the T-DNA inserted near the stop codon of the microsomal ascorbate peroxidase 3 (APX3, Bradi3g42340, I1I9A3) and was used as a T-DNA control

Experts in child psychiatry and autism conducted a record review of 40 patients to validate the autism diagnoses