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J Clin Endocrinol Metab (2008) 93:120310.10.1210/jc.2007-1986 28 TaboadaGFLuqueRMNetoLVMachado EdeOSbaffiBCDominguesRCet alQuantitative analysis of somatostatin receptor subtypes (1-5) gene expression levels in somatotropinomas and correlation to in vivo hormonal and tumor volume responses to treatment with octreotide LAR

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Hence, the acute low dose pharmacological NMDA-R blocker challenge mimics the broad symptomatology of schizophrenia and results in increased frontal glutamate in both animals and humans