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Additional recent studies have also identified nephrotoxic, neurotoxic and immunotoxic effects associated with mercury exposure, reported at doses or exposure levels at or lower than the exposure levels associated with the Fawer study

10.1038/mp.2016.133 58 HillhouseE

Downregulation of PGC1A can enhance the inflammatory response, increase ROS production, and lead to insulin resistance and glucose intolerance [85]

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The expression of matrix metalloproteinases, such as MMP2, MMP3, MMP8, and MMP9, are inhibited by DIM, leading to migration and invasion arrest [124]