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While Dihexa-specific desensitization kinetics haven't been thoroughly characterized in long-term studies, applying known c-Met receptor regulation patterns suggests daily dosing beyond 46 weeks without rest periods would likely produce diminishing returns

Pal et al., 2022)

Conclusion and perspectives Lactylation has emerged as a multifaceted regulatory mechanism that not only modulates gene transcription and signal transduction but also profoundly influences protein characteristics and functions