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Dimmeler, S

By inhibiting NF-kB activation, it could potentially reduce the inflammatory cascade that drives flare severity without compromising the immune response to concurrent infections, a common concern during lupus flares when patients may also be on immunosuppressive medications

CagriSema treatment resulted in substantially greater and clinically meaningful weight loss (-20.4%) than semaglutide alone (-14.9%), cagrilintide alone (-11.5%), or placebo (-3.0%), a finding consistent with at least partial additivity, although the study design does not permit a formal assessment of additive or synergistic effects

This results in an increased inflammatory response, which damages tissue cells, such as vascular ECs and pancreatic -cells, ultimately leading to Mets

When required, prescription details are verified with the prescriber before pharmacy dispensing