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Studies in which sleep deprivation (one or few nights) was applied to healthy humans during (mostly after) the immunological challenge of vaccination demonstrate that sleep deprivation reduced both the memory and effector phases of the immune response, as indexed by suppressed antigen-specific antibody and Th cell response compared with undisturbed sleep 117

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It gets harder the older you get, so its better to prevent aging than to try to reverse it. Youve noted some significant improvements in your dad, who began making changes very late in his life but now, at 80 years of age, has the vigor and mental stamina of a 30-year-old