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doi: 10.1016/j.freeradbiomed.2017.11.025 125 TamNNCGaoYLeungYKHoSM

4.5 Septicemia Bacterial inflammation triggers significant oxidative stress, during which the metabolism of oxidized phospholipids is regulated, at least in part, by mitochondrial -oxidation pathways ( 4.6 Effect on neonatal necrotizing enterocolitis The protective effects of levocarnitine supplementation against hypoxia/re-oxygenic necrotizing enterocolitis (NEC) have been demonstrated in young mice ( 4.7 Effect on neonatal respiratory distress syndrome Premature infants diagnosed with neonatal respiratory distress syndrome (RDS) exhibit significantly diminished plasma levels of L-carnitine compared to their non-RDS counterparts ( Emerging clinical evidence lends support to this concept across different intervention timepoints: Prenatal/Perinatal Strategy: A randomized study involving 100 pregnant women at high risk for preterm delivery compared prophylactic administration of L-carnitine plus dexamethasone versus dexamethasone alone

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In vitro , it has been demonstrated that insulin inhibits hepatic SHBG synthesis (59)