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3.2 HPA-axis dysregulation Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis constitutes a significant characteristic of major depressive disorder

Often called the body's "master antioxidant," L-Glutathione plays a key role in neutralizing free radicals and supporting cellular health

Thats where glutathione steps in - it sits inside the mitochondria like a live-in cleaner, mopping up reactive oxygen before it can cause chaos

Creatine supplementation may modestly increase serum creatinine levels, which reflects increased creatine metabolism rather than impaired kidney function

[DOI] [PMC free article] [PubMed] [Google Scholar] 179.Gast CE, et al