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Proc Natl Acad Sci U S A 2011;108:8674-9

Interestingly, the researchers found that lymphocytes in these patients had elevated levels of glutathione, which they hypothesize is a desperate, inadequate compensatory response by the cells trying to survive the relentless oxidative avalanche

Antacids and proton pump inhibitors such as Prilosec, Protonix, Prevacid, Aciphex, Zantac and Pepcid also can lead to B12 deficiency, because they reduce the stomach acid necessary to release the B12 from food

12 Now we recognize that ROS can be generated through mechanisms such as the mitochondrial electron transport chain, the endoplasmic reticulum, and NOX