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Nodular melanoma often doesn't meet standard abcde criteria Merkel Cell Carcinoma AEIOU: Asymptomatic Expanding rapidly Immune suppressed Older than 50 years Ultraviolet exposed site on fair skin (The most common clinical characteristics of Merkel cell carcinoma ) Ddx : Acneform Ursula A. Matulonis, MD Dana Farber Cancer Institute Boston, MA Melanoma mets in the upper GIT. Actinic cheilitis is a condition caused by long term sun exposure, leading to dry, cracked, and discolored lips, often a precursor to skin cancer. It's a reminder that our lips need sun protection

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