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Intestinal SCFAs can reach the liver through the hepatic portal vein

Antioxidants and CVD

Paired-end sequencing (26:98) was performed on the Illumina NextSeq500 platform using NextSeq500/550 High Output v2.5 (150 Cycles) reagents

Conclusion Collectively, the current study implied that supplementation of multistrain/multispecies synbiotic (250 mg/day) concomitant with L-carnitine (2 500 mg/day) for 8 weeks resulted in greater amendment in anthropometric and glycemic indices, and HDL-C in healthy female individuals with obesity without any severe side effects, indicating that L-carnitine + synbiotic co-supplementation seems to be more beneficial to ameliorate the mentioned parameters, compared with L-carnitine individual therapy