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The suppression of crucial pathways involved in safeguarding cells against ferroptosis, such as the GSH/GPX4 axis, has been associated with degeneration of motor neurons and progression of the disease in ALS

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In certain embodiments for parenteral administration, compositions are mixed with solubilizing agents such as CREMOPHOR , alcohols, oils, modified oils, glycols, polysorbates, cyclodextrins, polymers, and/or combinations thereof

And tick-borne infections can play into that too and the activation of the immune system