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The mechanisms of Se and selenoproteins in AD ferroptosis are complex, with cross-interactions among selenoproteins (details in Figure 8)

Study protocols and animal experiments performed in Zaragoza were approved by the Animal Experimentation Ethics Committee of the University of Zaragoza (numbers PI 18/2, PI 18/23, PI 62/22 and PI 24/25) and in accordance with institutional, national and European ethical animal regulations (Protection of Animals Act)

10.1016/j.jmb.2009.09.062 36 DeribeY

The hypopigmentation associated with PIH that develops after injury, burn, or other inflammatory condition may be permanent if the melanocytes in the area have been severely damaged or destroyed