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Subsequently, the skin sections with the scratching areas and adjacent regions were preserved in 4% paraformaldehyde for 24 h and then embedded in the paraffin wax

We identified the three main chondrocyte differentiation stages using previously described marker genes (Extended Data Fig

Each has documented limitations: NSAIDs: Reduce inflammation short-term but inhibit prostaglandin pathways needed for tissue repair

A base substitution in the exon of a collagen gene causes alternative splicing and generates a structurally abnormal polypeptide in a patient with Ehlers-Danlos Syndrome Type VII

Nonetheless, environmental stressors like UV radiation, heat, or air pollution can cause a surge in ROS levels, potentially leading to significant cellular damage 34