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AA-derived eicosanoids, including prostaglandins and leukotrienes, generally promote inflammatory signaling, leukocyte recruitment, and cytokine production (59)

P., Sisliyan C., Wong S., Zhang H., Forman H

The newly developed ferroptosis-associated therapeutic strategy possesses considerable promise for PF treatment

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Therefore, the observed upregulation of genes involved in mitochondrial function and lipid remodeling in our study may reflect an adaptive response that enhances mitochondrial fatty acid mobilization, thereby contributing to the metabolic flexibility of STn-positive gastric cancer cells and enabling them to better adapt and thrive in diverse metabolic environments