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Finally, we demonstrated that the previously unknown transsulfuration reaction from glutathione for -Glu-Ser-Gly synthesis was also present in iBMDM cells through [U- 13 C]-cysteine labeling experiment (Supplementary Figs

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26,154,235,236,237,238 From dysfunction to targeted interventions Cardiac dysfunction has profound hepatic effects

the untargeted metabolomics, on the other hand, is the unbiased and comprehensive approach that first detects distinct chromatographic features, such as mass-to-charge ratio, and subsequently identifies metabolites using the reference spectral library (Ribbenstedt et al., 2018)

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