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Can mask folate deficiency 5

If a patient is deficient in Folic Acid, it causes nerve damage & numbness of limbs (Peripheral Neuropathy)

Umbrella trials Type of clinical trial that evaluates multiple treatments or interventions simultaneously within the same overarching trial framework (for example, testing multiple novel therapies in a single trial in patients with Crohns disease)

IBD patients have been reported to express variants of the IL-23 receptor potentially accounting for excessive inflammation and the immune-mediated removal of commensal species in the gut (Duerr et al