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In vivo , intravenous injection of CRC cells into non-obese diabetic/severe combined immunodeficiency (NOD/SCID) mice showed that curcumin prevented lung metastasis formation in a miR-34a-dependent manner, suggesting curcumin induces mesenchymal-to-epithelial transition (MET) (27)

This material is supplied strictly for research and analytical purposes

Cell 23 , 207217 (2006)

Increased GSH availability is incompatible with early mouse development Increasing glutathione pools in vivo has been challenging due to the complex regulation of GSH synthesis