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doi: 10.1016/j.phymed.2023.154703

I have read articles before that suggested B12 deficiency could lead to cardiac symptoms

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DISCUSSION Our results are supportive of the concept that chronic exposure to tobacco results in the depression of cardiac function, which worsens even further in the setting of an acute MI

In a recent study, murine macrophages (RAW 264.7 cells and primary macrophages) were challenged with the enzyme, that caused IFN--mediated nitric oxide and TNF production to strengthen human defences (128)