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Within 2 weeks, PVN-OXT neurons stably expressed DREADDs, and activation of DREADDs in PVN-OXT neurons by the ligand clozapine-N-Oxide (CNO, 1 mg/Kg) increased neuronal firing and reduced heart rate and blood pressure [34, 49]

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The estimated prevalence of ME/CFS varies widely with the adopted diagnostic criteria, ranging from 1.41% (Oxford criteria) and 0.89% (Fukuda criteria) to 0.79% (Australian criteria) and 0.17% (Holmes criteria) [12]

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Cigarette tar mediates macrophage ferroptosis in atherosclerosis through the hepcidin/FPN/SLC7A11 signaling pathway

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