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A significant sign that the injections are working is a reduction in symptoms of vitamin B12 deficiency, such as weakness, rapid heart rate, easy bruising or bleeding, and pale skin

intercurrent events that occur after treatment initiation may affect the interpretation of results at the end of treatment

This method puts the vitamin into a muscle, usually in the arm or buttock

For instance, those with severe vitamin B12 deficiency may require weekly or biweekly shots until their blood levels return to normal