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[DOI] [PubMed] [Google Scholar] 127.Huang J.C., Su H.M., Wu P.Y., Lee J.J., Lee W.H., Chen S.C., Chiu Y.W., Hsu Y.L., Chang J.M., Chen H.C

10.1161/01.atv.19.5.1218 103 Ortiz de MontellanoP

Fourth line defense antioxidants The action of these antioxidants basically involves an adaptation mechanism in which they utilize the signals required for free radicals production and reaction to prevent the formation or reaction of such free radicals

Additionally, these treatments reversed the expression of key metabolic genes: downregulated genes such as Pgc1a and Glut2 , and upregulated genes like G6pc, Pck1, Sglt1, Dgat2, Fasn , and Scd , restoring them to levels comparable to those in lean mice (143)