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This is also true of certain xenobiotics and drugs [79]

However, multifocal occurrence of DT has been reported [2, 3]

doi: 10.1126/science.3375817, 132 SharonG.SampsonT

SARS-CoV-2 mainly destroys pulmonary surfactant-secreting type II alveolar cells (Wang et al., 2021a), that normally decrease the air/tissue surface tension and block TLR4 in the lungs, promoting ARDS and inflammation