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Currently, there is no specific laboratory or image testing that can be done to diagnose Fibromyalgia

Any hypothetical combination would likely require significantly lower doses of each compound than used in monotherapy

doi:10.1016/j.bbadis.2006.06.008 100

Berberine (500 mg) A powerhouse botanical compound that helps regulate glucose metabolism, lower insulin resistance, and promote fat loss naturally often compared to metformin for its metabolic effects

Other research has highlighted its protective effects on the gastrointestinal (GI) tract, including accelerated healing of ulcers and mitigated damage from toxins