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Such bidirectional control becomes particularly relevant in chronic pain, where thalamic plasticity alters connectivity, excitability, and rhythmicity, leading to thalamocortical dysrhythmia that amplifies nociceptive salience and sustains persistent pain (81, 82)

Add water to emulsify, rinse thoroughly, then follow with a water-based cleanser if desired

St Paul M, Saibil SD, Kates M, Han S, Lien SC, Laister RC, et al

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