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Description

Rutin attenuates metabolic changes, nonalcoholic steatohepatitis, and cardiovascular remodeling in high-carbohydrate, high-fat diet-fed rats

Increased sensitivity to targeted therapy and chemotherapy The ferroptosis mechanism provides a new approach to overcoming resistance in chemotherapy and targeted therapy

Studies have shown that under hyperoxic conditions, mitochondria in pulmonary epithelial cells exhibit significant structural and functional abnormalities, with a marked decrease in the activity of respiratory chain complexes I and IV, inhibition of oxidative phosphorylation, and alterations in mitochondrial morphology, such as vacuolization and cristae fragmentation (Garcia et al., 2021