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Next, we evaluated differences in -diversity using principal coordinates analysis plots and found differences in -diversity (defined as a difference in intergroup diversity 60 ) between rotenone compared to non-rotenone-exposed groups, and mice with CPT1 inhibition compared to no inhibition (P479L+R, Wt+R+E, PARK2, PARK2+E and PARK2+R+E groups) (Supplementary Fig

Their meta-analysis included 51 studies with 20,907 cases and 23,905 controls

The highest binding affinity for GPx4 with a docking score of 7.6kcal/mol and greater ligand exposure was exhibited by Lapatinib, which bonded with the enzyme at ASP165 and TYR169 residues

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