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The study observed a direct proportionality between the applied dose and modifications in SOD and CAT activities, as well as MDA levels within cells 93

Zur Anwendung kommt in der klinischen Praxis hufig Pirenzepin/Gastrozepin 25-50 mg/d (Anticholinergikum mit relativ selektivem Antagonismus an M1- und M4-Rezeptoren) [5], das wirksam ist, aber die Gefahr der Zunahme der anticholinergen Nebenwirkungen von Clozapin (bis zum Ileus, siehe unten) erhht

Long-term safety data beyond 12 months is limited

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