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Chronic high-dose vitamin B intake (generally in gram quantities daily over many months) has been linked to severe sensory neuropathy characterized by numbness, impaired proprioception, and paresthesia in a stocking-glove distribution

In conclusion, the temporal proteomic profiling performed in this study defines a clear developmental roadmap for liver organoids, offering actionable insights for optimizing their use in drug metabolism, toxicological testing, and disease modeling

In: Kramer K, Hoppe P, Packer L, eds

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