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As GPx4 and FACL4 act as opposing regulators of ferroptosis, disrupted GPx4 and FACL4 expression would therefore promote the susceptibility of hepatocytes to ferroptotic cell death (27)

[DOI] [PubMed] [Google Scholar] 5.Arciero PJ, Gardner AW, Calles-Escandon J, Benowitz NL, Poehlman ET

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Potential Research Applications: Glucose metabolism and insulin signaling pathway studies Mitochondrial function and cellular energy regulation research Metabolic pathway modulation and energy homeostasis models Mitochondrial-derived peptide activity and cellular signaling investigations For laboratory research use only