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Description

These agents cause sinoatrial (SA) and atrioventricular (AV) nodal depression and a decrease in myocardial contractility (nondihydropyridines)

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In preclinical studies published in Endocrinology, researchers found that chronic administration of AOD-9604 reduced body weight and body fat in obese mice while increasing beta-3 adrenergic receptor expression to levels comparable with lean mice