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Lehrer RI, Ganz T: Endogenous vertebrate antibiotics

Isotopically labeled metabolic substrates were used to monitor generation of 3 H 2 O from glycolysis or beta oxidation and 14 CO 2 from the pentose phosphate pathway, glutamine utilization, or TCA cycle

As we get older, our natural supply of GHK-Cu decreases, which contributes to the visible signs of aging

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Parallel research on NAD biology (e.g., precursors like NR/NMN) reinforces the centrality of NAD to mitochondrial output and recoverymechanistically aligned with 5-Amino-1MQs NNMT inhibition (Cant et al., Cell Metabolism )