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The most frequently reported adverse events (3%-10% of adult patients) following injection of BOTOX for severe primary axillary hyperhidrosis in double-blind studies include injection-site pain and hemorrhage, nonaxillary sweating, infection, pharyngitis, flu syndrome, headache, fever, neck or back pain, pruritus, and anxiety

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Preservation occurs through the inclusion of 0.9% benzyl alcohol, which inhibits bacterial reproduction by disrupting microbial cell membrane activity

Experiments running for several weeks or months require a stable compound