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Test results showed that the oral administration of PNE mediated a decrease in the abundance of Streptococcus intestinalis and an increase in the transgenic metabolite l-arginine, which further inhibited osteoblasts and enhanced osteoclasts through the gutbone axis, exerting a significant anti-osteoporotic effect

Functional enrichment and PPI analysis The Metascape database ( is a web-based portal that integrates more than 40 biological information databasesthrough a simple interface for one-click, quick analysis, comprehensive data analysis can be easily obtained 17

"Nobody knows what's in it, so there's a question of purity of what you're getting," Tan said

TDP-43 is recruited to stress granules in conditions of oxidative insult