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Trends Pharmacol Sci 44(3):137149 Saha S et al (2025) Elucidating the role of Nrf2 signaling pathway in Mycoplasma infections

Overall survival varies from a few months to decades, but on average death occurs between 2.5 and 5 years from the diagnosis (Masrori and Van Damme, 2020)

p62/SQSTM1 is required for the protection against endoplasmic reticulum stress-induced apoptotic cell death

The LANDO pathway is particularly essential for recycling microglial A receptors, such as TREM2, and its disruption is known to exacerbate neurodegeneration in AD models [175]